IZI1

USD 34.39
Updated: Oct 24, 2026

About this item

Source Naturals SAMe is a stable, bioavailable form of S-adenosyl-L-methionine. These tablets are enteric coated and blister packed to prevent breakdown and inactivation of the ingredients. Dozens of clinical studies have demonstrated that SAMe supports joint comfort, function and mobility in the spine, hips and knees. It is important to the joints because of its critical role in cartilage formation. Studies also show that SAMe helps support a positive outlook. It is able to cross the blood-brain barrier where it affects the synthesis and activation of various proteins, such as neurotransmitters. SAMe is known as a "methyl donor." This means that it works by giving up a piece of itself (a methyl group consisting of one carbon and three hydrogen atoms) to other molecules. Methylation plays a part in many critical cellular functions. SAMe is present in every living cell in the body. However, levels of SAMe tend to decline with age.

  • Features
    • Double strength
    • Enteric coated
    • 400 mg per tablet

Specifications

Ingredient

Amount per serving / Daily value %

SAMe (S-adenosyl-methionine) from 800 mg of SAMe disulfate tosylate

400 mg / †

Other Ingredients

cellulose, methacrylic acid copolymer, mannitol, citric acid, stearic acid, silica, hydroxypropyl methylcellulose, triacetin, sodium starch glycolate, modified cellulose gum.

Other Information

Contains no yeast, dairy, egg, gluten, soy or wheat., Contains no sugar, preservatives, or artificial flavor or fragrance.

Product photos are for illustrative purposes only and are exemplary. The colors, inscriptions, parameters, dimensions, sizes, functions, and/or any other features of the original products may look different than in reality due to their visual characteristics, so please refer to the product features that are indicated in the product descriptions.

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